In Vivo Transfection

In vivo Magnetofection has been designed for in vivo targeted transfection and transduction. This original system combines magnetic nanoparticles and nucleic acid vectors that are retained after injection at the magnetically targeted site. In this way, systemic distribution is minimized and toxicity is reduced.

Several specialized reagents have been developed:

• In vivo ViroMag - for in vivo targeted transduction with any viral vector
• In vivo PolyMag - cationic polymer-based reagent for in vivo targeted transfection of nucleic acids
• In vivo DogtorMag - cationic lipid-based reagent for in vivo targeted transfection of nucleic acids
• In vivo SilenceMag - for in vivo transfection of small RNA into target cells/tissue
• BrainFectIN - for in vivo nucleic acid delivery into the central nervous system

Starter kits and trial kits that include magnet sets are available for select reagents. The magnet sets are sold separately as well.