ViroMag Viral Gene Delivery Reagent

ViroMag Transduction Reagent is a magnetic nanoparticles formulation designed to increase virus infection and transduction capacities. It is suitable for all viruses.

Based on the Magnetofection technology, this reagent allows concentration of the complete applied dose of viral particles onto cells within minutes, inducing a significant improvement of virus transduction with extremely low vector doses. Due to its specific properties, ViroMag is ideal for infecting non-permissive cells. No molecular biology processes or biochemical modifications are required. 

ViroMag must be used with a magnetic plate. Two starter kits are available that include a Super Magnetic Plate (8x12cm) or a 96-Place Magnetic Plate (8x12cm). Magnetic plates can also be purchased separately.

Figure 1: ViroMag enhances adenoviral infection. K562, PBL and NIH-3T3 cells were infected with an adenovirus alone (Ad-LacZ) or with complexes of adenovirus and 3 µl of ViroMag. Cells were submitted or not to magnetic field and beta-Galactosidase expression was determined 24H after infection.

Figure 2: Time Course of HIV Infection with or without ViroMag.